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Author: Admin | 2025-04-28
The medications most commonly associated with tardive dyskinesia include antipsychotic medications called neuroleptics. Neuroleptics help treat psychotic disorders (severe mental health disorders in which a person loses touch with reality) and some mood disorders (like depression and bipolar disorder). Tardive dyskinesia can also occur as a side effect of some medications used to treat nausea and digestive disorders. This article will discuss which medications are associated with tardive dyskinesia and its symptoms and treatment. Robert Brook / Getty Images Medicines That Cause Tardive Dyskinesia The medications that can cause tardive dyskinesia affect the nervous system. While these medications can be very helpful for treating certain conditions, some of the effects on the nervous system may cause the side effect of tardive dyskinesia. It’s important to be aware that this side effect does not affect everyone who takes these medications, and there may be some genetic factors that affect the risk. Tardive dyskinesia can be mild, moderate, or severe. Antipsychotic DrugsTardive dyskinesia affects approximately 15%–30% of people being treated with antipsychotic drugs long term. Each year, about 5.5% of people taking first-generation antipsychotics experience tardive dyskinesia. Most Common Many different medications can cause tardive dyskinesia, but this side effect is most associated with first-generation antipsychotics, also called typical neuroleptics or typical antipsychotics. These medications are used to treat schizophrenia, as well as mood disorders and anxiety. Examples of first-generation antipsychotics causing tardive dyskinesia include: Haldol (haloperidol)Mellaril (thioridazine)Prolixin (fluphenazine)Stelazine (trifluoperazine)ChlorpromazineTrilafon (perphenazine) Less Common Atypical antipsychotics, which are also described as second-generation antipsychotics, can cause tardive dyskinesia, but this side effect is less common than with first-generation antipsychotics. Additionally, some antidepressants and medications used for neurological disorders, digestive issues, and congestion can cause this side effect. Examples include:Second-generation antipsychotics: Abilify (aripiprazole) Barhemsys (amisulpride), Invega (paliperidone), and Risperdal (risperidone)Antidepressants and mood stabilizers: Anafranil (clomipramine), Cymbalta (duloxetine), Desyrel (trazodone), Elavil (amitriptyline), lithium, Prozac (fluoxetine), and Sinequan (doxepin)Antiepileptic drugs (AEDs): Dilantin (phenytoin), Lamictal (lamotrigine), and Tegretol (carbamazepine)Movement disorder medications: Abilify (aripiprazole), Artane (trihexyphenidyl), and pimozideAntiemetics (antinausea medications): Compazine (prochlorperazine) and Reglan (metoclopramide)Decongestants: Sudafed (pseudoephedrine) and Sudafed PE Congestion (phenylephrine) When you start taking a new medication, check the label to familiarize yourself with the list of side effects. Symptoms of Tardive Dyskinesia Dystonia is a type of movement disorder characterized by involuntary muscle movements, and it can be caused by neurological disorders or by medication. Tardive dyskinesia is a type of dystonia that occurs as a medication side effect. It is not possible to stop the motor symptoms of tardive dyskinesia. Symptoms can be very distressing for people who are experiencing them and for their loved ones. Sometimes people are not aware that they are experiencing tardive dyskinesia. Some of the most common symptoms of tardive dyskinesia include repetitive and purposeless involuntary movements of the mouth, face, tongue, and hands. This can include repeatedly: Sticking out the tonguePuckering or smacking the lipsMaking mouth and jaw movementsEyelid or eyebrow movementsOpening the eyes wide or shutting them tightlyTwisting of the hands, fingers, or feetPurposeless movements of the neck,
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