Comment
Author: Admin | 2025-04-28
Age: Administer dose over ≥10 minutes.IV Administration (Ibuprofen Lysine)Administer by IV infusion using IV port nearest to the IV insertion site.Do not infuse simultaneously through same line as parenteral nutrition solutions. If same line must be used, interrupt infusion of the nutrition solution for 15 minutes before and after administration of ibuprofen; maintain line patency by infusing dextrose injection or sodium chloride injection.Avoid extravasation (irritating to extravascular tissues).DilutionDilute ibuprofen lysine injection with an appropriate volume of dextrose injection or sodium chloride injection.Administer within 30 minutes of preparation; discard any unused solution.Rate of AdministrationAdminister dose over 15 minutes.DosageDosage of ibuprofen lysine expressed in terms of ibuprofen.To minimize the potential risk of adverse cardiovascular and/or GI events, use lowest effective dosage and shortest duration of therapy consistent with the patient’s treatment goals. Adjust dosage based on individual requirements and response; attempt to titrate to the lowest effective dosage. Pediatric PatientsDosage in children should be guided by body weight.Inflammatory DiseasesJuvenile Rheumatoid ArthritisOral30–40 mg/kg daily divided into 3 or 4 doses. 20 mg/kg daily in divided doses may be adequate for children with mild disease.Once clinical effect obtained, reduce dosage to lowest level that maintains adequate symptomatic control.If dosage >30 mg/kg daily, carefully monitor for signs and symptoms of early liver dysfunction.PainOralFor mild to moderate pain in children 6 months to 2 years of age, 10 mg/kg every 6–8 hours; avoid disrupting the child's sleep pattern. (See Pediatric Use under Cautions.)See Table 1 for recommended analgesic dosages for self-medication in children 6 months to 11 years of age.Dose may be administered every 6–8 hours. Table 1. Age- or Weight-Based Dosage for Self-medication of Minor Aches and Pain in Children 6 Months to 11 Years of Age164179189212213AgeWeightDose6–11 months12–17 pounds (approximately 5–8 kg)50 mg12–23 months18–23 pounds (approximately 8–10 kg)75 mg2–3 years24–35 pounds (approximately 11–16 kg)100 mg4–5 years36–47 pounds (approximately 16–21 kg)150 mg6–8 years48–59 pounds (approximately 22–27 kg)200 mg9–10 years60–71 pounds (approximately 27–32 kg)200–250 mg11 years72–95 pounds (approximately 33–43 kg)300 mgFor self-medication of minor aches and pain in adolescents ≥12 years of age, 200 mg every 4–6 hours; may increase dosage to 400 mg every 4–6 hours
Add Comment