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Author: Admin | 2025-04-28
Contraindications. Do not give with citalopram. Increased risk of serotonin syndrome with other serotonergic drugs (eg, SSRIs, SNRIs, triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, meperidine, methadone, tryptophan, buspirone, amphetamines, St. John's Wort) or with drugs that impair serotonin metabolism (eg, MAOIs, linezolid, IV methylene blue). Avoid alcohol. Increased risk of bleeding with concomitant NSAIDs, aspirin, warfarin, and others that affect coagulation. May be antagonized by carbamazepine. Caution with drugs metabolized by CYP2D6 or other centrally-acting drugs. Increases metoprolol levels. Lexapro Adverse Reactions Adverse Reactions Insomnia, ejaculation disorder, nausea, increased sweating, fatigue, somnolence, decreased libido, anorgasmia. Lexapro Clinical Trials See Literature Lexapro Note Lexapro Patient Counseling See Literature Lexapro Generic Name & Formulations General Description Escitalopram (as oxalate) (single-isomer citalopram) 5mg, 10mg+, 20mg+; tabs (+scored). Pharmacological Class SSRI. See Also How Supplied Tabs—100; Soln—contact supplier Storage Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15 to 30°C (59° to 86°F). Manufacturer Mechanism of Action The mechanism of antidepressant action of escitalopram, the S-enantiomer of racemic citalopram, is presumed to be linked to potentiation of serotonergic activity in the CNS resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT). Lexapro Indications Indications Major depressive disorder (MDD). Lexapro Dosage and Administration Adult Initially 10mg once daily; may increase to max 20mg once daily at an interval of no less than 1 week. Elderly or hepatic impairment: 10mg once daily. Children Lexapro Contraindications Contraindications During or within 14 days of MAOIs; do not start an MAOI during or within
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