Since celecoxib is predominantly metabolised by CYP2C9 it should be used at half the recommended dose in patients receiving fluconazole. Concomitant use of 200 mg single dose of celecoxib and 200 mg once daily of fluconazole, a potent CYP2C9 inhibitor, resulted in a mean increase in celecoxib C max of 60% and in AUC of 130%. Concomitant use of
Nabumetone: 1,000mg qd: 1,000mg bid: 2,000mg/day (qd or divided bid) Cox-2 inhibitors Low Dose Medium Dose High or Max Dose; Celecoxib/Celebrex: 200mg qd:
Since celecoxib is predominantly metabolised by CYP2C9 it should be used at half the recommended dose in patients receiving fluconazole. Concomitant use of 200 mg single dose of celecoxib and 200 mg once daily of fluconazole, a potent CYP2C9 inhibitor, resulted in a mean increase in celecoxib C max of 60% and in AUC of 130%. Concomitant use of
Since celecoxib is predominantly metabolised by CYP2C9 it should be used at half the recommended dose in patients receiving fluconazole. Concomitant use of 200 mg single dose of celecoxib and 200 mg once daily of fluconazole, a potent CYP2C9 inhibitor, resulted in a mean increase in celecoxib C max of 60% and in AUC of 130%. Concomitant use of
Since celecoxib is predominantly metabolised by CYP2C9 it should be used at half the recommended dose in patients receiving fluconazole. Concomitant use of 200 mg single dose of celecoxib and 200 mg once daily of fluconazole, a potent CYP2C9 inhibitor, resulted in a mean increase in celecoxib C max of 60% and in AUC of 130%. Concomitant use of
Co-administration of celecoxib with an aluminum- and magnesium-containing antacid resulted in a reduction in plasma celecoxib concentrations with a decrease of 37% in C max and 10% in AUC. Celecoxib, at doses up to 200 mg twice daily can be administered without regard to timing of meals.
Since celecoxib is predominantly metabolised by CYP2C9 it should be used at half the recommended dose in patients receiving fluconazole. Concomitant use of 200 mg single-dose of celecoxib and 200 mg once daily of fluconazole, a potent CYP2C9 inhibitor, resulted in a mean increase in celecoxib C max of 60% and in AUC of 130%. Concomitant use of
by S Videla 2024 Cited by 45celecoxib alone. After PK parameters adjusted according to reference dose, mean celecoxib C max with CTC (313.33 ng ml–1) was lower than with celecoxib alone (
APX-Celecoxib. Brand name: APX-Celecoxiba. Form strength: celecoxib 200 mg capsule, 30. Manufacturer: Apotex Pty Ltd. Dispensed price for max qty: $17.87. Max
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