TIVDAK caused changes in the corneal epithelium and conjunctiva resulting in changes in vision, including severe vision loss, and corneal ulceration. 1 PADCEV [package insert]. Northbrook, IL
The most common adverse reactions to Tivdak include nausea, diarrhea, peripheral neuropathy, hair loss, rash and dry and irritated eyes. The package insert includes a warning about more severe eye problems that can lead to vision loss.
Package insert. Hospira; 2024. 19. Cefazolin. Package insert. GSK; 2024. 20. Ceftriaxone. Package insert. Sandoz; 2024. 21. Daptomycin. Package insert
Tivdak 40 mg as a lyophilized cake or powder in a single-dose vial for reconstitution: xx VII. References 1. Tivdak [package insert]. Bothell, WA; Seagen, Inc; January 2024. Accessed January 2024. 2. Referenced with permission from the NCCN Drugs Biologics Compendium (NCCN Compendium ) tisotumab vedotin.
C. Absence of unacceptable toxicity from the drug. Examples of Tivdak [package insert]. Bothell, WA; Seagen, Inc; January 2024
insert (Dextenza). J1300 eculizumab (Soliris). J1301 edaravone (Tivdak). J9281 (mitomycin pyelocalyceal instillation (Jelmyto). J9299
Dexamethasone ophthalmic insert 0.4 mg, 0.1 mg (Dextenza), $145.48 Tisotumab vedotin-tftv for injection, for intravenous use, 1mg (Tivdak)
Tivdak (tisotumab vedotin-tftv) is a tissue factor (TF)-directed antibody drug conjugate (ADC). Tivdak [package insert]. Bothell, WA: Seagen
drug conjugates containing vedotin, including Tivdak. Among 1 TIVDAK [package insert]. Bothell, WA: Seagen, Inc. 2 Cancer Stat
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