Winchester JF, Salsberg JA: Drugs removed by dialysis and hemoperfusion; updated tables. List of Issues; Collections; Issue Topics Editorials; For Authors
Drug removal during dialysis is frequently of interest to those caring for patients receiving hemodialysis or peritoneal dialysis. The extent of drug dialyzability determines whether supplemental dosing is necessary during or following dialysis. The accompanying table is a reference regarding the effect of either form of dialysis on drug clearance.
Drug removal during dialysis is frequently of interest to those caring for patients receiving hemodialysis or peritoneal dialysis. The extent of drug dialyzability determines whether supplemental dosing is necessary during or following dialysis. The accompanying table is a reference regarding the effect of either form of dialysis on drug clearance.
examine the effects of high permeability dialysis on drug dialyzability. Results of these studies confi rm predictions that drug removal from plasma is often enhanced as compared with more traditional dialysis membranes. Studies with high permeability dialysis also demonstrate that removal of drug from plasma often exceeds
Dialysis and drug clearance. Patients on dialysis are subject to extracorporeal clearance of small molecules, including many drugs. The extent to which dialysis removes a particular drug from plasma is dependent on its water solubility, molecular weight, protein binding and volume of distribution.3 Many reference sources contain lists of drugs
500 mg once daily, 33% removed with HD. On days of dialysis dose after dialysis. DOSING IN PERITONEAL DIALYSIS. DOSING IN PERITONEAL DIALYSIS
Phosphate binders prevent the buildup of phosphorus in the body, since very little is removed during dialysis. medication list. Check with your
Patients on dialysis are subject to extracorporeal clearance of small molecules, including many drugs. The extent to which dialysis removes a particular drug from plasma is dependent on its water solubility, molecular weight, protein binding and volume of distribution. 3 Many reference sources contain lists of drugs cleared by dialysis (Box).
U- Indicates that no published data exist but physicochemical characteristics of the drug suggest that significant drug removal is Unlikely during dialysis. L - Indicates that no published data exist but physicochemical characteristics of the drug suggest that significant drug removal is Likely during dialysis.
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