In patients with vasodilatory shock vasopressin in therapeutic doses increases systemic vascular resistance and mean arterial blood pressure and reduces the dose requirements for norepinephrine. Vasopressin tends to decrease heart rate and cardiac output. The pressor effect is proportional to the infusion rate of exogenous vasopressin.
Commonly used vasoactive drugs Adrenaline (bolus or infusion) Noradrenaline (infusion only) Vasopressin (infusion only) Metaraminol (bolus or infusion).
of the additive and the infusion rate will depend upon the dose regimen of the prescribed Vasopressin analogues such as desmopressin, oxytocin, vasopressin
The initial vasopressin infusion rate was 0.014 0.007 units/kg/hr and the maximum dose was 0.032 0.016 units/kg/hr (Figure 1). Average duration of vasopressin infusion was 64.6 4.2 hours. None of the patients developed NEC while on vasopressin and only 10% were diagnosed with sepsis within 72 hours prior to receiving vasopressin.
alternative vasopressor (e.g. vasopressin) is superior to vasopressin adrenaline treatment: reduce the infusion rate (or stop infusion if severe).
Plasma levels of vasopressin of 30 pg.ml 1 were achieved when the infusion rate of vasopressin was reduced to 0.01 U.min 1. Six patients maintained adequate perfusion pressures with vasopressin as the sole pressor. Discontinuation of vasopressin infusion caused a sudden decrease in arterial pressure.
infusion rate will depend upon the dose regimen of the prescribed drug. Infusion to patients treated with drugs leading to an increased vasopressin effect.
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Dilution and dose of vasopressin infusion for septic shock is different from that for INFUSION RATE GUIDE (concentration 200
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