Citrate lock

Catheter lock solution, anti-clotting and antimicrobial is one of the innovations from Dirinco. Citra-Lock is recommended in the European Renal Best Practice Guidelines (ERBP) and the American Society of Diagnostic and Interventional Nephrology (ASDIN). Citra locks have been extensively studied. Citra-Lock is effective in maintaining catheter patency. The Citrate lock is

Additional serious adverse effects associated with high concentrations of citrate lock solutions continue to be reported worldwide. 58–60 The FDA currently recommends a lower citrate concentration of 4% for use in catheter locks. 61 The ERBP also recommend a citrate 4% solution given its preferable benefit/risk ratio compared to higher

25 Mai et al. evaluated the efficacy of AMLs and found that citrate based locks could reduce the risk of CRBSI as compared with heparin-based locks. Additionally, citrate locks were effective in reducing exit site infection in non-tunneled HDC. 28. Several devices are developed to reduce CRSBI such as ClearGuard HD cap and GRIP-LOK.

There are advantages to citrate lock that make it a desirable option. One is that citrate has been associated with a lower bleeding event rate. Fewer systemic bleeding events were found using 4% citrate lock (7 in 32 patients) versus heparin lock (5000 U/ml) (21

by DA Pierce 2024 Cited by 28trisodium citrate (also known as sodium citrate or citrate) has recently been shown to be an efficacious alternative to heparin as a locking solution.

An antimicrobial-containing citrate lock is better than a heparin lock in the prevention of catheter-related infection, while citrate alone fails to show a similar advantage.

Background: Due to its reported antimicrobial effects, hypertonic citrate (46.7%) is a widely used catheter lock solution, but following instillation, citrate inevitably spills into the systemic circulation. This process is mainly driven by hydraulic effects during instillation and density differences between blood and lock solution.

Citra-Lock is a pure citrate lock solution and the best alternative for heparin catheter lock. Improves catheter patency as in many published clinical trials. Dirinco has become an expert in extracorporeal circulation treatment of renal failure and catheter lock solutions. Dirinco AG. Wilenstrasse 24 8832 Wilen B. Wollerau Switzerland.

The Citrate lock is based on tri-sodium citrate and can be safely used in all catheters! Citra-Lock 5ml vials 4% – 30% -46,7%; Citra-LockS 2 x 2,5 ml (prefilled syringe) 4% Citra-LockS prefilled syringe. Citra-Lock 4% Twin-Pack, 2 x 2,5 ml in 5 ml syringe. Art.nr.