Respiratory depression. Similar to some other opioids, a risk of respiratory depression is associated with methadone use, though the
Methadone produces respiratory depression by direct action on brain stem respiratory centers. The respiratory depression involves a
Serious, life-threatening, or fatal respiratory depression may occur with use of methadone. The peak respiratory depressant effect of methadone occurs later and
Respiratory depression is the chief hazard associated with methadone hydrochloride administration. respiratory depression and opioid withdrawal, timing
Methadone is contraindicated in any patient who has or is suspected of having a paralytic ileus. WARNINGS. Respiratory Depression Respiratory depression is the chief hazard associated with methadone hydrochloride administration. Methadone's peak respiratory depressant effects typically occur later, and
depression (link) warned that benzodiazepines and opioids can both cause respiratory depression, the respiratory depression effect of methadone may be
Methadone produces respiratory depression by direct action on brain stem respiratory centers. The respiratory depression involves a
Respiratory depression is the chief hazard associated with methadone hydrochloride administration. Methadone's peak respiratory depressant
Respiratory depression is the chief hazard associated with methadone hydrochloride administration. Methadone's peak respiratory depressant effects typically
Depression can cause disturbed sleep.
It becomes a terrible and terrifying negative feedback loop.