Allopurinol dose renal
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Allopurinol. Allopurinol has a renally excreted active metabolite that accumulates in renal impairment and may cause adverse effects if the dose is not adjusted
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Renal-dosing of allopurinol compounds the poor management of gout and adds to the perception that allopurinol may be detrimental for renal
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Alternatively, colchicine Lowering the starting dose of allopurinol appropriate to the level of renal function reduces the risk of allopurinol.
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Table 1. Suggested Dosing of Allopurinol . Treatment should be initiated on a dose of allopurinol adjusted according to renal function. Then the dose of
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Alternatively, colchicine Lowering the starting dose of allopurinol appropriate to the level of renal function reduces the risk of allopurinol.
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4 Allopurinol dose needs to be adjusted in renal failure. Maximum daily dose of allopurinol is 800 mg/day. Dose adjustments may be necessary if allopurinol
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Allopurinol. Allopurinol has a renally excreted active metabolite that accumulates in renal impairment and may cause adverse effects if the dose is not adjusted
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Use: For the chronic management of hyperuricemia in patients with gout who have an inadequate experience to a maximally titrated dose of allopurinol, who are intolerant to allopurinol, or for whom treatment with allopurinol is not advisable. Renal Dose Adjustments. Mild to Moderate Renal Dysfunction: No adjustment recommended
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doses in patients with renal insufficiency because of the risk of allopurinol hypersensitivity. Gradual allopurinol dose escalation, in
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