Methotrexate. Omeprazole may increase the effects of methotrexate. Your doctor may adjust your dose depending on the levels of methotrexate in your body.
Both Methotrexate and Aceclofenac can increase the risk of nephrotoxicity. Omeprazole. Omeprazole decreases the clearance of Methotrexate (high-dose)
Omeprazole taken with clopidogrel can lower the activity of clopidogrel, so avoid taking these drugs together. Taking omeprazole with methotrexate may result in high levels of methotrexate or methotrexate toxicity. Your doctor may temporarily stop omeprazole treatment if you are taking a high dose of methotrexate.
PRILOSEC (omeprazole) Delayed-Release Capsules and PRILOSEC. (omeprazole Methotrexate: PRILOSEC may increase serum levels of methotrexate. (7.7).
Clopidogrel: omeprazole reduces effectiveness of clopidogrel. Omeprazole and clopidogrel are metabolised by the same enzyme (CYP2C19). 10; Methotrexate: omeprazole increases exposure to methotrexate as it inhibits renal elimination of methotrexate. 11; Lansoprazole Indications. Like omeprazole, lansoprazole is another type of proton pump inhibitor.
What is Omeprazole? Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,462 Omeprazole users for its effectiveness, alternative drugs and more. What is Methotrexate? Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.
Hepatic insufficiency: − Omeprazole: In − Methotrexate - PPIs possibly reduce excretion of methotrexate, leading to an increased risk.
interactions: co-administration of methotrexate and omeprazole has resulted in delayed renal elimination of methotrexate. In one case in which methotrexate was
PRILOSEC (omeprazole) Delayed-Release Capsules and PRILOSEC. (omeprazole Methotrexate: PRILOSEC may increase serum levels of methotrexate. (7.7).
Hence Omeprazole being a much more expensive drug than it is now.....