Alkylating agents are a class of chemotherapy drugs used in the treatment of cancer. These chemical compounds work by adding alkyl groups (such as methyl or
Alkylating agents represent an important class of anticancer drugs. The occurrence and emergence of tumor resistance to the treatment with alkylating agents denotes a severe problem in the clinics. A detailed understanding of the mechanisms of activity of alkylating drugs is essential in order to overcome drug resistance.
Electrophilic, soluble alkylating agents are often toxic and carcinogenic, due to their tendency to alkylate DNA. This mechanism of toxicity is relevant to the function of anti-cancer drugs in the form of alkylating antineoplastic agents. Some chemical weapons such as mustard gas (sulfide of dichloroethyl) function as alkylating agents
The categories are Alkylating Agents, Nitrosoureas, Antimetabolites, Antitumor Antibiotics, Plant Alkaloids, and Steroid Hormones. ALKYLATING AGENTS are drugs
Alkylating Agents (CCNS):. Alkylating agents are cell cycle non specific drugs which contain alkyl groups that form reactive molecular
ALKYLATING-DRUG. subject field: medicine: drugs Some examples of alkylating drugs are Leukeran, Cytoxan, thiotepa and busulfan.
Alkylating agents are a common class of chemotherapy drugs that work by transferring alkyl groups to DNA, causing cross-linkages and strand
Chemotherapy with medications known as alkylating agents Alkylating drugs work by damaging the DNA of cancer cells. However
Classes of chemotherapy drugs used for lymphoma include alkylating agents, plant alkaloids, anthracyclines, and proteasome inhibitors. Alkylating agents such as
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