Losartan is metabolized in the liver to an active metabolite (which has a similar action to losartan). The time to peak effect after a dose is 1-2 hours for losartan and 3-4 hours for the metabolite. At its peak level, losartan inhibits 85% of the effects of angiotensin II, and 25 to 40% of this inhibition persists for 24 hours.
The time to peak effect after a dose is 1-2 hours for losartan and 3-4 hours for the metabolite. At its peak level, losartan inhibits 85% of the
The time to peak effect after a dose is 1-2 hours for losartan and 3-4 hours for the metabolite. At its peak level, losartan inhibits 85% of the
The time to peak effect after a dose is 1-2 hours for losartan and 3-4 hours for the metabolite. At its peak level, losartan inhibits 85% of the
Losartan is metabolized in the liver to an active metabolite (which has a similar action to losartan). The time to peak effect after a dose is 1-2 hours for losartan and 3-4 hours for the metabolite. At its peak level, losartan inhibits 85% of the effects of angiotensin II, and 25 to 40% of this inhibition persists for 24 hours.
Peak areas were recorded for all the peaks. The amount of losartan potassium was computed from the peak area by use of the formula: Amount of losartan
Furthermore, losartan does not inhibit ACE (kininase II), the enzyme that Mean peak concentrations of losartan and its active metabolite are
Losartan: Losartan inhibits systolic and diastolic pressor responses to angiotensin II infusions. At peak, 100 mg of losartan potassium inhibits these responses
Losartan should be used with caution in patients with bilateral Mean peak concentrations of losartan and its active metabolite are
Comments
A mountain peak
Taking a peek
A fit of pique