The obinutuzumab group had more side effects than the rituximab group in the GALLIUM trial. Obinutuzumab is only available as an intravenous
Per the prescribing information, obinutuzumab (Gazyva) is contraindicated in patients with known hypersensitivity reactions (e.g, anaphylaxis) to obinutuzumab or any of the excipients, including serum sickness with prior obinutuzumab use. Per the prescribing information, obinutuzumab (Gazyva) carries the following warnings and precautions:
The side effects listed below relate to treatment with Obinutuzumab alone. If you are having Obinutuzumab in combination with chemotherapy, we
Learn about the side effects of obinutuzumab, from common to rare, for consumers and healthcare professionals.
What are the possible side effects of obinutuzumab? easy bruising, unusual bleeding, purple or red spots under your skin; weakness, cough
Laboratory testing of obinutuzumab showed that compared with rituximab, the Fc region of obinutuzumab is more effective at recruiting effector immune cells (antibody-dependent cellular
Although obinutuzumab improved PFS, it did not improve OS, and, as noted by editorialists, it is unclear whether a component of the improved obinutuzumab response rates relate to the higher doses of obinutuzumab versus rituximab. Nevertheless, these data support obinutuzumab plus chemotherapy as an option for front-line therapy in FL.
However, it also shows that undesirable side effects are more common with obinutuzumab than with with induction therapy, and that the adverse
Obinutuzumab 1000mg from a medical oncologist and being an Indian side effects. This medicine is not recommended for children and
Comments
one of my own pet peeves, sorry