Amiodarone side effects elderly

Amiodarone is a powerful anti-arrhythmic drug. However, its use is somewhat limited by side-effects. No study examining side-effects specifically in elderly patients exists. We have reviewed noncardiac side-effects in 61 elderly patients on long-term oral amiodarone treatment (follow-up 3-66 months)

These effects are often dose-related and occur more often in elderly patients than in younger patients. Areas of Uncertainty. The side effects of low-dose amiodarone therapy (200 mg daily) in

When elderly patients are administrated with amiodarone, cardiologists and pharmacists should carefully evaluate the long-term and short-term side effects, as well as whether combined use with other drugs will increase the adverse reactions of amiodarone.

Common Amiodarone Side Effects in Elderly Patients. Amiodarone is a medication frequently prescribed to elderly patients to manage cardiac arrhythmias effectively. However, this powerful drug is not without its side effects, and understanding these side effects is crucial for elderly individuals and their healthcare providers.

Amiodarone is a powerful anti-arrhythmic drug. However, its use is somewhat limited by side-effects. No study examining side-effects specifically in elderly patients exists. We have reviewed noncardiac side-effects in 61 elderly patients on long-term oral amiodarone treatment (follow-up 3-66 months)

by M Mahadevappa 2024adverse effects associated with the amiodarone therapy being almost 15 Amiodarone-induced hyponatremia in an elderly patient. Eur. Geriatric Med

by M Turrin 2024 Cited by 2Drug-induced lupus: simvastatin or amiodarone? A case report in elderly. Side effects of long-term amiodarone therapy. Circulation 2024; 67:

Amiodarone is a potent inhibitor to a number of drug metabolizing enzymes and drug transporters, including CYP3A4, CYP2C9, and P-glycoprotein. In addition, the expected hepatic, thyroid and pulmonary side effects of amiodarone are much more pronounced in the elderly population.

When elderly patients are administrated with amiodarone, cardiologists and pharmacists should carefully evaluate the long-term and short-term side effects, as well as whether combined use with other drugs will increase the adverse reactions of amiodarone.