The risk for trimethoprim-associated hyperkalemia is greatest in patients Bacter-Aid DS/Bactrim/Bactrim DS/Septra/Septra DS/Sulfamethoxazole
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Also, the trimethoprim component (one of the active ingredients in Bactrim and Bactrim DS) may lead to hyperkalemia (high levels of potassium in
In addition to an elevated creatinine, Bactrim is also associated with hyperkalemia. The mechanism is felt to be a decreased aldosterone-
The increase in creatinine associated with TMP is mild: 10% and reversible with drug discontinuation. The mechanism of Bactrim induced hyperkalemia is via Trimethoprim inhibition of the sodium channel located on the luminal surface of the principal cells, independent of aldosterone blockade.
Bactrim and Bactrim DS (sulfamethoxazole and trimethoprim) [prescribing information]. Hyponatremia and/or hyperkalemia in patients treated with the
Hyperkalemia can be a side effect of the antibiotic Bactrim. monitoring antibiotics pharmacist Comments.
The mechanism of Bactrim induced hyperkalemia is via Trimethoprim inhibition of the sodium channel located on the luminal surface of the principal cells, independent of aldosterone blockade. ( Same site of action of amiloride, triameterene and pentamidine).
Medscape - Indication-specific dosing for Bactrim, Bactrim DS, Septra, Septra Treatment with recommended doses may cause hyperkalemia when trimethoprim is
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