Benadryl first trimester cleft palate

Research data suggests there is mixed evidence of Cleft palate and microcephaly with use of Nitrofurantoin in first trimester.

Safest course: Avoid in 1st trimester ; later trimesters unknown. Primidone (Benadryl). Antihistamine. B. Yes. 1st trimester – cleft palate

cleft lip and cleft palate. Avoid Claritin D and Zyrtec D (antihistamines combined with pseudoephedrine), especially during the first trimester.

Sulfonamides increase the risk of heart disease, cleft palate, cleft lip, and jaundice, and are avoided during the first trimester and before

There are rare reports of cleft palate/cleft lip with metronidazole exposures in the first trimester, but the rate of malformations may not be any different.

There are rare reports of cleft palate/cleft lip with metronidazole exposures in the first trimester, but the rate of malformations may not be any different.

Flagyl is safe during the second and third trimesters of pregnancy. However during the first trimester the flagyl can cause cleft palate.

First-trimester screening Cleft lip and palate Nonchromosomal abnormalities Midsagittal view Cleft lip and palate (CLP) is a major contributor to fe-tal defects. It is found in

Pregnancy and Breastfeeding. Cleft lip with or without cleft palate has been reported following first trimester exposure to Metronidazole, however, most