The two classes of drugs used for changes in memory are acetylcholinesterase inhibitors and NMDA receptor agonists. ACETYLCHOLINESTERASE INHIBITORS. Drug names:.
by SE Tomek 2024 Cited by 85These ligands include the NMDA receptor modulators memantine and acamprosate, as well as the partial NMDA agonist D-cycloserine. Data collected
NMDA agonist; also non selective mGlu agonist: 0114: NMDA: Selective NMDA agonist: 0312 -(Tetrazol-5-yl)glycine: Highly potent NMDA agonist: View all NMDA Receptor
The activation of NMDA receptors requires co-agonist binding of glycine/D-serine and glutamate; therefore, antagonists that disrupt co-agonist binding, effectively block the NMDA activity. The hyper-phosphorylation and resulting overactivation of NMDA receptors is well-established in PD; and is implicated in the worsening of dyskinesias 16 18 .
Progesterone, androgen and estrogen receptor agonists Potassium channel blocking and opening drugs; : N-Methyl-D-aspartic acid (NMDA) receptor
by SE Tomek 2024 Cited by 85These ligands include the NMDA receptor modulators memantine and acamprosate, as well as the partial NMDA agonist d-Cycloserine.
reported that sarcosine is an NMDA receptor co-agonist that differs from glycine, suggesting that co-agonistic activity at the NMDA receptors of sarcosine may, in part, be involved in the clinical benefits of this drug in schizophrenia. Nonetheless, all these findings suggest that GlyT-1 inhibition could be a novel pharmacotherapeutic target
We compared the effect of treating SE with a single drug to those of combinations including a GABAA agonist, an NMDA antagonist and an
by MDB Swedberg 2024 Cited by 15antagonists, NMDA antagonists, and other drugs with psychoactive or hallucinogenic properties in humans. Cannabinoid receptor agonists like
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